16 March 2010

Practical measures for personal longevity

Filed under: aging, supplement, UKH+, UKTA — David Wood @ 12:06 pm

What steps do you take, to enhance your personal longevity?

That’s a question I still struggle to answer.  I believe that the next few decades will see  spectacular advances in science, technology, society, art, and culture, and I’d very much like to participate in these – in some cases as an observer, and in some cases as an engineer and activist.  Rationally, therefore, I should be taking steps to make it more likely that I will remain alive, fit, and healthy, throughout these coming decades.  But what are these steps?

That’s the topic of the UKH+ (Extrobritannia) meeting that will be taking place in London on the afternoon of Sunday 28th March: “Aging and dietary supplements – correcting some myths“.  The speaker will be Michael Price, who has been carrying out independent research for 30 years into questions of life extension and futurism.  The meeting is described as follows on the Extrobritannia meetings blog:

This talk will review where we are (and aren’t) with respect to understanding aging. It will cover theories of aging, and the (largely failed) promises of gerontologists and immortalists, past and present. It will then make some suggestions for what we can do now – including a discussion of which dietary supplements may work, which may not, and why dietary supplements are generally discredited.

The idea of a “pill to make you live longer” is alluring, and often drums up tabloid headlines.  A Google search for “pill to make you live longer” returns more than 900,000 results.  Some websites look more credible than others.  In addition to pills, these websites often talk about “superfoods”.  For example, the Maximum Life Foundation recently published an article “Seven Superfoods That Will Keep You Young” and listed the following:

  1. Whey Protein
  2. Raw, Organic Eggs
  3. Leafy Greens
  4. Broccoli
  5. Blueberries
  6. Chlorella
  7. Garlic, the “Stinking Rose”

The same article continues:

The Most Important Way to Slow Aging

Do you know what the number one way to slow aging in your body is? If you’re like most people, you don’t.

Most people don’t understand the importance of optimizing their insulin levels, as insulin is without a doubt THE major accelerant of aging. Fortunately, you can go a long way toward keeping your insulin levels healthy by reducing or eliminating grains and sugars from your diet.

This one crucial step, combined with nutritional typing and the inclusion of nature’s anti-aging miracle foods in your diet, can dramatically improve your health and longevity.

It is also crucial to include a comprehensive exercise program as that is another lifestyle choice that will radically improve the sensitivity of your insulin receptors and help to optimize your insulin levels.

Theories about superfoods, pills, and other dietary supplement, depend in turn on theories of the causes of aging.  Some of these theories remain controversial – and I expect Michael will review the latest findings.  These theories include (to quote from Wikipedia, emphasis added):

  • Telomere theory: Telomeres (structures at the ends of chromosomes) have experimentally been shown to shorten with each successive cell division. Shortened telomeres activate a mechanism that prevents further cell multiplication. This may be an important mechanism of ageing in tissues like bone marrow and the arterial lining where active cell division is necessary. Importantly though, mice lacking telomerase enzyme do not show a dramatically reduced lifespan, as the simplest version of this theory would predict;
  • Free-Radical Theory: The idea that free radicals (unstable and highly reactive organic molecules, also named reactive oxygen species or oxidative stress) create damage that gives rise to symptoms we recognize as ageing.

Given the rich variety of different advice, it may be tempting – especially for people who are still in the first few decades of their lives – to take a different approach to hoping for a long life.  This approach is to trust that technological and medical improvements will happen quickly enough to be usefully applicable to you later in your life.  For example, someone in their twenties today can judge it as likely that significant improvements in anti-aging techniques will be widely available before they reach the age of sixty.

After all, life expectancy continues to rise.  Figures released last year by the UK’s Office of National Statistics (PDF) state that:

  • Life expectancy for males in the UK, at birth, was 73.4 years, in 1991-1993;
  • This figure rose to 77.4 in 2006-2008;
  • That’s a 4.0 year increase in life expectancy over that 15 year period.

People can follow the lead of anti-aging researcher Aubrey de Grey and talk about a future “longevity escape velocity” in which the increase in life expectancy over a 15 year period would be at least 15 years.  That’s an attractive vision, and de Grey makes a persuasive argument that it is credible.  What is far less certain, however, is:

  • The future timescale in which such remedies will become available;
  • Any variability in the performance of these future remedies, which might be influenced by the amount of damage our bodies have accumulated in the meantime.

These reservations increase the importance of addressing personal longevity issues sooner rather than later.  I’m reminded of the quotation that is attributed to Theodore Roosevelt:

Old age is like everything else. To make a success of it, you’ve got to start young

Finally, I’ll return to the question posed at the start of this article:

What steps do you take, to enhance your personal longevity?

At present, here’s my answer:

  • Have an annual medical checkup, to detect early warning signs of impending trouble;
  • Take (on doctor’s prescription) a statin pill in the evening, to lower cholesterol;
  • Take a collection of pills in the morning, including ginseng, mutivitamins, garlic, and ginkgo biloba;
  • “5 a day” portions of fruit and vegetables;
  • Pay attention to gum health, by cleaning between teeth as well as the teeth themselves;
  • Keep fit, by walking, and (increasingly) by spending time on the golf course or golf driving range;
  • Avoid cigarettes and excess alcohol;
  • Avoid dangerous sports.

I may have a different answer, after listening to Michael’s talk at the end of the month.

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